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Apr 1 – 5, 2019
Fairmont Château Laurier Hotel
UTC timezone

Radiation imagers for quantitative, single-particle digital autoradiography of alpha-and beta-particle emitters for targeted radionuclide therapy

Not scheduled
Fairmont Château Laurier Hotel

Fairmont Château Laurier Hotel


Dr Brian Miller (University of Colorado School of Medicine)


Over the last several years new quantitative digital autoradiography imaging tools have been developed that are sensitive to both alpha- and beta-particle emitters. These include scintillation-, gaseous-, and semiconductor-based radiation-detection technologies that localize the emission location of charged particles on an event-by-event basis at resolutions up to 20 µm FWHM. These imaging systems allow radionuclide activity concentrations to be quantified to unprecedented levels (mBq/µg) and provide simultaneous, real-time imaging capabilities of both high- and low-activity samples without dynamic range limitations that plague traditional autoradiography. Additionally, large-area imagers are available (>20 × 20 cm2) to accommodate high-throughput imaging studies. This presentation reviews the various detector technologies and their associated performance trade-offs to provide targeted alpha therapy researchers with an overview of the current technologies available for selecting an optimal detector configuration to meet imaging requirement needs.
Email Address
Presentation Type Contributed Oral

Primary author

Dr Brian Miller (University of Colorado School of Medicine)

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